Giant cell urothelial carcinoma is a rare variant of bladder cancer recognized by the current World Handriers Health Organization classification of urologic tumours.It is an aggressive tumour with a poor prognosis that usually presents at an advanced stage.It is characterized histologically by pleomorphic giant cells.
We discuss a case of giant cell urothelial carcinoma presenting Play Mat at an early stage in a previously well 62-year-old woman.Histology showed a tumour comprising pancytokeratin positive bizarre mononuclear and multi-nuclear giant cells admixed with areas of conventional urothelial carcinoma and carcinoma in situ.Three-month follow-up cystoscopy and magnetic resonance imaging showed no evidence of recurrence or pelvic lymphadenopathy.